1.
Gastroenterology
; 162(7):S-57-S-58, 2022.
Article
in English
| EuropePMC | ID: covidwho-1904843
2.
J Crit Care
; 62: 46-48, 2021 04.
Article
in English
| MEDLINE | ID: covidwho-939047
ABSTRACT
Patients with COVID-19 ARDS have distinct physiological and immunological phenotypes compared to patients with non-COVID ARDS. Patients with COVID-19 ARDS (n = 32) had a significant improvement in PaO2: FiO2 ratio (p = 0.046) following low-dose steroid treatment, unlike patients with non-COVID ARDS (n = 16) (p = 0.529). Patients with COVID-19 ARDS had a greater fall in CRP compared to patients with non-COVID ARDS, albeit not statistically significant (p = 0.07). Our novel findings highlight differences in the underlying physiological and immunological phenotypes between COVID-19 and non-COVID ARDS, with implications for future ARDS studies.
Subject(s)
Anti-Inflammatory Agents/therapeutic use , COVID-19 Drug Treatment , COVID-19/physiopathology , Respiratory Distress Syndrome/drug therapy , Respiratory Distress Syndrome/physiopathology , Steroids/therapeutic use , Adult , Aged , C-Reactive Protein/drug effects , Female , Humans , Hydrocortisone/therapeutic use , London/epidemiology , Male , Methylprednisolone/therapeutic use , Middle Aged , Phenotype , Respiratory Mechanics , Retrospective Studies , SARS-CoV-2
3.
Br J Anaesth
; 126(1): e44-e46, 2021 01.
Article
in English
| MEDLINE | ID: covidwho-898523